About Multiple Sclerosis | About the Accelerated Cure Project | About Music to Cure MS
About Multiple Sclerosis
Multiple Sclerosis, or MS, is a chronic demyelinating disorder of the central nervous system affecting over 400,000 people in the US and 2 million individuals worldwide.
In MS, for an unknown reason the immune system attacks myelin, a material which insulates the nerves of the central and autonomic nervous systems, ultimately leaving multiple "sclera" - scars - on the lining of the nerves.
Much as sap rises directly under the bark of a tree, nerves transmit their electrical impulses directly beneath that insulating myelin sheath. When the sheath is damaged, "short circuits" occur, and the signal is broken or scrambled.
This affects the entire Central Nervous System - brain and spine - with results that are varied and unpredictable, differing for each patient, and even from day to day in the same patient.
Symptoms include sensory (e.g. touch, kinesthesia and vision), motor, and cognitive (including emotional) problems, affecting all parts of the body and mind. Meanwhile, the brain itself - gray matter as well as white nerve cells - shrinks as injury accumulates.
MS commonly results in disability, including the inability to walk, impaired vision or blindness, cognitive dysfunction, bladder and bowel problems, disabling fatigue and other serious symptoms. Unfortunately, no one knows what causes Multiple Sclerosis, there is no known cure for the disease, and treatments are modest at best. The Accelerated Cure Project is one step towards finding a better way to treat, and ultimately to cure, this disease.
About the Accelerated Cure Project for Multiple Sclerosis
Accelerated Cure Project for Multiple Sclerosis is a national nonprofit organization dedicated to curing MS by determining its causes.
Its major success is the creation of a large-scale, multidisciplinary MS Repository of blood samples and data from people with MS and matched controls. With the help of funds raised by efforts like Music to Cure MS, samples are being collected at sites across the United States.
These samples are currently being used by over 52 studies investigating the causes of MS and related autoimmune problems. In exchange for access to the repository, researchers agree to return the data they generate from the samples so that results from disparate experiments can be combined.
Accelerated Cure Project began by developing a Cure Map to establish and document what is and is not known about the causes of MS. Using the Cure Map, Accelerated Cure Project began to facilitate the research most likely to reveal the causes of MS in the shortest time through use of the MS Repository.
For more information about the Accelerated Cure Project or to make a corporate or individual contribution, call 781/487-0008, or visit www.accelerated cure.org.
Visit the ACP Stay Connected form to sign up for their email list.
About Music to Cure MS
Multiple Sclerosis (MS) is the most common disabling neurological condition affecting young adults worldwide. All of us who have this chronic, incurable, progressive, disabling disease, or who know someone who has it, are eager to support research towards ending its affects.
To raise funds, some people hold bike or foot races. Some sell fancy shoes, or hold scavenger hunts, or plan rock concerts. Marion Leeds Carroll, a former opera singer and stage director who was diagnosed with MS in 1988, heard about the Accelerated Cure Project in 2002 and decided to use her own skill-set to bring opportunities to her own world: classical music.
The first fundraising concerts she organized were called "Sing to Cure MS", but it soon became clear that musicians other than singers were eager to take part.
"Music to Cure MS" has provided opportunities for supporing this vital research to:
- classical-music performers
- audiences - whether or not they already love classical music
- local businesses - who gain publicity with
- program ads
- silent auction donations
- concert-day refreshment donations
- other performing groups, which can exchange advertisements in our program / web site